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Medicinal Herb Info

Medicinal Herb Info

Fagara

Contents:

Common Names | Parts Usually Used | Plant(s) & Culture | Where Found | Medicinal Properties | Biochemical Information
Legends, Myths and Stories | Uses | Formulas or Dosages | How Sold | Warning | Resource Links

Scientific Names

fagara

  • Zanthoxylum zanthoxyloides
  • Fagara zanthoxyloides
  • Zanthoxylum senegalense
  • Zanthoxylum tessmannii
  • Fagara tessmannii

Common Names

  • Fagara
  • Prickly Ash
  • Rapeko (Moore)
  • Guene gui deg (Wolof)
  • Wo (Bambara)
  • Gozo ngua (Bambara)
  • Fasahuari (Hausa)
  • Dori (Toucouleur)
  • Wouho (Djoula)

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Parts Usually Used

The root bark, stem bark, leaves, and fruits are used medicinally. The aromatic roots are particularly valued.
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Description of Plant(s) and Culture

fagara

Fagara species are shrubs or small trees that grow up to 6-8 meters tall (sometimes reaching 12 meters), with spiny trunks and branches. The bark is grey to beige with fine vertical fissures and woody prickle-bearing protuberances. The slash is yellow and aromatic. The leaves are alternate, compound with 5-7 leaflets, and aromatic when crushed. Flowers are small, white or greenish, arranged in loose panicles. The fruits are small follicles containing black shiny seeds.
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Where Found

Native to:

  • West Africa (particularly Nigeria, Ghana, Burkina Faso)
  • Central Africa
  • Eastern Africa
  • Southern Africa
  • North Africa (Saharan Maghreb)
  • Western Asia (Arabian Peninsula)
  • Southwestern Europe

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Medicinal Properties

fagara

  • Antisickling (for sickle cell disease)
  • Antimicrobial and antibacterial
  • Antidiarrheal
  • Antihypertensive
  • Anti-inflammatory
  • Analgesic
  • Antidepressant
  • Antioxidant
  • Anticancer
  • Antidiabetic
  • Antimalarial
  • Antiparasitic
  • Antifungal
  • Antitrachoma
  • Phosphodiesterase-inhibiting
  • Antihistaminic

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Biochemical Information

Major active compounds include:

  • Alkaloids:
    • Berberine
    • Fagaronine
    • Chelerythrine
    • Skimmianine
    • Nitidine
  • Phenolic acids:
    • Vanillic acid
    • Syringic acid
    • p-hydroxybenzoic acid
  • Divanilloylquinic acids (Burkinabins A, B, C)
  • Coumarins
  • Essential oils
  • Lignans

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Legends, Myths and Stories

Fagara rubescens is known for its aromatic properties. When the leaves or bark of the plant are crushed or bruised, they release a distinct fragrance that is often described as spicy or citrus-like. This aroma contributes to its appeal and may have cultural significance in certain regions.
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Uses

Traditional medicinal uses include:

  • Treatment of sickle cell anemia
  • Management of malaria and fever
  • Relief from toothache and oral infections
  • Treatment of digestive disorders
  • Management of bacterial and fungal infections
  • Relief from arthritis and rheumatism
  • Treatment of diabetes
  • Management of hypertension
  • Treatment of cardiovascular conditions

Other uses:

  • Chewing sticks for dental hygiene
  • Spice and food seasoning
  • Construction materials
  • Fish poison
  • Insecticide

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Formulas or Dosages

Limited research for specific dosage recommendations. Traditional preparations include:

  • Root or bark decoctions
  • Leaf infusions
  • Root powder
  • Aqueous extracts

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How Sold

  • Dried root bark
  • Dried stem bark
  • Powdered preparations
  • Herbal extracts
  • Traditional medicines

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Warning

  • High doses may cause liver and kidney damage
  • May interact with diabetes medications
  • Not recommended during pregnancy or breastfeeding
  • May affect blood pressure – use with caution if taking antihypertensive medications
  • May cause seizures at very high doses
  • Some species contain toxic compounds – proper identification is crucial
  • The plant is endangered in some regions due to overharvesting

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Resource Links

Top Herbs to Support Sickle Cell Anemia Symptoms Naturally

HealthLine – 4 Herbs for Sickle Cell Anemia

Phytomedicine – Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae)

National Library of Medicine – Acute toxicity effects of the methanolic extract of Fagara zanthoxyloides (Lam.) root-bark

National Library of Medicine – Effects of Root Extracts of Fagara zanthoxyloides on the In Vitro Growth and Stage Distribution of Plasmodium falciparum

ScienceDirect – Chapter Three – Phytochemistry and antibacterial potential of the genus Fagara

Frontiers in Pharmacology – Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia

ScienceDirect – Effects of stem bark aqueous extract of Fagara tessmannii Engl (Rutaceae) on cardiovascular risks related to monosodium glutamate-induced obesity in rat: In vivo and in vitro assessments

The Green Institute – Fagara rubescens

Zanthoxylum zanthoxyloides

African Journal of Traditional, Complementary and Alternative Medicines – THE NIGERIAN ZANTHOXYLUM; CHEMICAL AND BIOLOGICAL VALUES

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