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The Medicinal Herb Info site was created to help educate visitors about the often forgotten wisdom of the old ways of treating illnesses. Many of today's drugs and medicines were originally derived from natural ingredients, combinations of plants and other items found in nature.

We are not suggesting that you ignore the help of trained medical professionals, simply that you have additional options available for treating illnesses. Often the most effective treatment involves a responsible blend of both modern and traditional treatments.

We wish you peace and health!

Fagara

Scientific Names

fagara

  • Zanthoxylum zanthoxyloides
  • Fagara zanthoxyloides
  • Zanthoxylum senegalense
  • Zanthoxylum tessmannii
  • Fagara tessmannii

Common Names

  • Fagara
  • Prickly Ash
  • Rapeko (Moore)
  • Guene gui deg (Wolof)
  • Wo (Bambara)
  • Gozo ngua (Bambara)
  • Fasahuari (Hausa)
  • Dori (Toucouleur)
  • Wouho (Djoula)

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Parts Usually Used

The root bark, stem bark, leaves, and fruits are used medicinally. The aromatic roots are particularly valued.
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fagara

Description of Plant(s) and Culture

Fagara species are shrubs or small trees that grow up to 6-8 meters tall (sometimes reaching 12 meters), with spiny trunks and branches. The bark is grey to beige with fine vertical fissures and woody prickle-bearing protuberances. The slash is yellow and aromatic. The leaves are alternate, compound with 5-7 leaflets, and aromatic when crushed. Flowers are small, white or greenish, arranged in loose panicles. The fruits are small follicles containing black shiny seeds.
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Where Found

Native to:

  • West Africa (particularly Nigeria, Ghana, Burkina Faso)
  • Central Africa
  • Eastern Africa
  • Southern Africa
  • North Africa (Saharan Maghreb)
  • Western Asia (Arabian Peninsula)
  • Southwestern Europe

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Medicinal Properties

fagara

  • Antisickling (for sickle cell disease)
  • Antimicrobial and antibacterial
  • Antidiarrheal
  • Antihypertensive
  • Anti-inflammatory
  • Analgesic
  • Antidepressant
  • Antioxidant
  • Anticancer
  • Antidiabetic
  • Antimalarial
  • Antiparasitic
  • Antifungal
  • Antitrachoma
  • Phosphodiesterase-inhibiting
  • Antihistaminic

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Biochemical Information

Major active compounds include:

  • Alkaloids:
    • Berberine
    • Fagaronine
    • Chelerythrine
    • Skimmianine
    • Nitidine
  • Phenolic acids:
    • Vanillic acid
    • Syringic acid
    • p-hydroxybenzoic acid
  • Divanilloylquinic acids (Burkinabins A, B, C)
  • Coumarins
  • Essential oils
  • Lignans

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Legends, Myths and Stories

Fagara rubescens is known for its aromatic properties. When the leaves or bark of the plant are crushed or bruised, they release a distinct fragrance that is often described as spicy or citrus-like. This aroma contributes to its appeal and may have cultural significance in certain regions.
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Uses

Traditional medicinal uses include:

  • Treatment of sickle cell anemia
  • Management of malaria and fever
  • Relief from toothache and oral infections
  • Treatment of digestive disorders
  • Management of bacterial and fungal infections
  • Relief from arthritis and rheumatism
  • Treatment of diabetes
  • Management of hypertension
  • Treatment of cardiovascular conditions

Other uses:

  • Chewing sticks for dental hygiene
  • Spice and food seasoning
  • Construction materials
  • Fish poison
  • Insecticide

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Formulas or Dosages

Limited research for specific dosage recommendations. Traditional preparations include:

  • Root or bark decoctions
  • Leaf infusions
  • Root powder
  • Aqueous extracts

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How Sold

  • Dried root bark
  • Dried stem bark
  • Powdered preparations
  • Herbal extracts
  • Traditional medicines

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Warning

  • High doses may cause liver and kidney damage
  • May interact with diabetes medications
  • Not recommended during pregnancy or breastfeeding
  • May affect blood pressure – use with caution if taking antihypertensive medications
  • May cause seizures at very high doses
  • Some species contain toxic compounds – proper identification is crucial
  • The plant is endangered in some regions due to overharvesting

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Resource Links

Top Herbs to Support Sickle Cell Anemia Symptoms Naturally

HealthLine – 4 Herbs for Sickle Cell Anemia

Phytomedicine – Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae)

National Library of Medicine – Acute toxicity effects of the methanolic extract of Fagara zanthoxyloides (Lam.) root-bark

National Library of Medicine – Effects of Root Extracts of Fagara zanthoxyloides on the In Vitro Growth and Stage Distribution of Plasmodium falciparum

ScienceDirect – Chapter Three – Phytochemistry and antibacterial potential of the genus Fagara

Frontiers in Pharmacology – Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia

ScienceDirect – Effects of stem bark aqueous extract of Fagara tessmannii Engl (Rutaceae) on cardiovascular risks related to monosodium glutamate-induced obesity in rat: In vivo and in vitro assessments

The Green Institute – Fagara rubescens

Zanthoxylum zanthoxyloides

African Journal of Traditional, Complementary and Alternative Medicines – THE NIGERIAN ZANTHOXYLUM; CHEMICAL AND BIOLOGICAL VALUES

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