Skip to content
  • Home
  • Herb Index
  • Resources
  • Credits & About This Site
  • CAUTION!
  • Shop For Carefully Curated Herb Products
Medicinal Herb Info

Medicinal Herb Info

Chinese Skullcap

Contents:

Common Names | Parts Usually Used | Plant(s) & Culture | Where Found | Medicinal Properties | Biochemical Information
Legends, Myths and Stories | Uses | Formulas or Dosages | Nutrient Content | How Sold | Warning | Resource Links

Scientific Names

Chinese Skullcap

  • Scutellaria baicalensis Georgi
  • Scutellaria baicalensis

Common Names

  • Chinese Skullcap
  • Baikal Skullcap
  • Hooded Skullcap
  • Huang Qin – Chinese
  • Hwanggeum – Korean
  • Kikin – Japanese
  • Shchitovidka baykalskaya – Russian
  • Escutelaria de Baikal – Spanish
  • Scutellaire de Baïkal – French
  • Chinesischer Helmkraut – German

Back to Top


Parts Usually Used

The dried root is the primary medicinal part used, often referred to as Radix Scutellariae or Huang Qin in Traditional Chinese Medicine. The roots are typically harvested in spring or fall, then dried and processed into powders, tinctures, pills, or used in their natural form for decoctions.
Back to Top


Description of Plant(s) and Culture

Chinese Skullcap is a perennial herbaceous plant belonging to the mint family (Lamiaceae). The plant typically grows 30-120 cm tall with a diameter of 2.5-3 mm. It has an elongated, branching, thick, fleshy rhizome up to 2 cm in diameter. The stem base is about glabrous or sessile to puberulent, blunt-tetragonal in form, and appears finely striped. The base can be either green or purple.

The leaves are 1.5-4.5 cm long and 0.5-1.2 cm wide, lanceolate to linear-lanceolate in shape. The lower part of the leaf is a lighter shade of green than the top, with petioles approximately 2 mm long. The plant produces blue, purple-red, and purple corollas that are 2.3-3 cm long, arranged in terminal racemes 7-15 cm long that often congregate into panicles at the apex of stems. The fruits are oblong, dark brown, 1.5 mm tall, and 1 mm in diameter.
Back to Top


Where Found

Chinese Skullcap is native to several East Asian countries and regions including China, Korea, Mongolia, Japan, and the Russian Far East (including Eastern Siberia, Amur Oblast, and Primorye). It has been intentionally cultivated and propagated in numerous European and American countries.

The plant thrives on dry terrain and sunny grassy slopes at altitudes of 60-2000 meters. It is abundantly distributed throughout China, particularly in Heilongjiang, Liaoning, Inner Mongolia, Hebei, Henan, Gansu, Shanxi, Shandong, and Sichuan provinces. China is the main producer of Scutellaria baicalensis for medicinal use.
Back to Top


Medicinal Properties

Chinese Skullcap has been extensively studied and demonstrates a wide range of pharmacological activities including anti-inflammatory, antioxidant, anti-cancer, neuroprotective, hepatoprotective, antimicrobial, antiviral, cardiovascular protective, and immune-modulating effects.

In Traditional Chinese Medicine, Chinese Skullcap is considered to have bitter and cold properties, with effects of clearing away heat and dampness, eliminating fire pathology, detoxifying, and preventing bleeding and fetal restlessness. According to TCM theory, it is associated with the lung and liver meridians.

Modern pharmacological research has confirmed many traditional uses, showing that the plant’s flavonoids can inhibit pro-inflammatory cytokines and enzymes, providing significant anti-inflammatory activity. The herb also demonstrates promising antiviral properties, with studies indicating that baicalin can inhibit the replication of certain viruses including influenza and herpes viruses.
Back to Top


Biochemical Information

Chinese Skullcap contains a diverse array of phytochemical constituents, with more than 100 compounds identified. The major bioactive components include:

Flavonoids (Primary active compounds):

  • Baicalin (C21H18O11) – the most abundant flavonoid and primary bioactive compound
  • Baicalein (C15H10O5) – the aglycone form of baicalin
  • Wogonoside
  • Wogonin (C16H12O5)
  • Scutellarin
  • Scutellarein
  • Oroxylin A (C16H12O5)
  • Norwogonin
  • Chrysin
  • Various glycosides and glucuronides

Other compounds:

  • Volatile oils (including acetophenone, palmitic acid, oleic acid)
  • Terpenoids (with antibacterial, antiviral, and anti-inflammatory effects)
  • Polysaccharides (water-soluble, mainly composed of arabinose, galactose, and glucose)
  • Amino acids (14 types, with proline being the most abundant)
  • Sterols (α-spinasterol and β-sitosterol)
  • Phenolic compounds
  • Lignin glycosides
  • Trace elements

Back to Top


Legends, Myths and Stories

Chinese Skullcap has a rich history dating back over 2000 years in Traditional Chinese Medicine. It was first recorded in the Shennong Bencaojing (The Classic of Herbal Medicine), written between 200-250 AD during the Han Dynasty, for treatment of bitter, cold, lung, and liver problems.

The name “Huang Qin” has significant meaning in Chinese culture: “Huang” (黄) means yellow, referring to the golden-yellow color of the dried root, while “Qin” (芩) is equivalent to “Jin” (金), meaning golden herb. This etymology reflects the plant’s valued medicinal properties and distinctive appearance.

Li Shizhen, the famous author of Bencao Gangmu (Compendium of Materia Medica), first published in 1593, reported his successful self-administration of Chinese Skullcap to treat a severe lung infection when he was 20 years old, demonstrating the confidence traditional practitioners had in this herb.
Back to Top


Uses

Traditional medicinal uses include treatment of:

  • Diarrhea and dysentery
  • Hypertension
  • Hemorrhaging and bleeding disorders
  • Insomnia and sleep disorders
  • Inflammation and inflammatory conditions
  • Respiratory infections including pneumonia and flu
  • Fever and cold symptoms
  • Jaundice and liver conditions
  • Headache and abdominal pain
  • Bacterial and viral infections
  • Cancer (various types)
  • Cardiovascular diseases
  • Neurological disorders

Modern clinical applications:

  • Osteoarthritis (in combination with other herbs)
  • Hepatitis and liver protection
  • Diabetes management
  • Cancer treatment (as adjuvant therapy)
  • Neuroprotection in neurodegenerative diseases
  • Cardiovascular protection
  • Immune system support
  • Anti-aging applications

Animal husbandry applications:

  • Feed additive to improve growth performance in livestock
  • Treatment of mastitis in dairy cattle
  • Prevention of bacterial and viral diseases in animals
  • Improvement of meat quality and antioxidant capacity
  • Stress reduction in farm animals

Industrial and cosmetic applications:

  • Antibacterial plastics and composite materials
  • UV-resistant silk products
  • Cosmetic ingredients for whitening and anti-aging
  • Natural preservatives

Chinese Skullcap is frequently used in classical prescriptions such as Mahuang Shengma decoction, Xiexin decoction, and Huangqin decoction. In modern clinical practice, it appears in over 477 prescriptions for treating 153 main diseases, with cold and cough being the most frequent applications.
Back to Top


Formulas or Dosages

Note: There isn’t enough reliable information to establish standardized dosing recommendations for Chinese Skullcap. Clinical studies in humans are limited, and most research has been conducted in laboratory settings or animal models.

Traditional preparations:

  • Decoctions (boiling dried root in water)
  • Tinctures and liquid extracts
  • Powdered root preparations
  • Pills and tablets
  • Capsules

Research dosages from animal studies:

  • For hepatoprotective effects: 50-100 mg/kg baicalin
  • For anti-inflammatory effects: 20-100 mg/kg various compounds
  • For neuroprotective effects: 50-100 mg/kg baicalin
  • For cardiovascular protection: 30-60 mg/kg baicalein
  • For antioxidant activity: 25-70 mg/kg various compounds

Human studies (limited data):

  • For osteoarthritis: Herbal formulations containing Chinese Skullcap at 500 mg/day have been studied
  • Safety studies: 100-2800 mg baicalein as single oral dose showed good tolerability in healthy volunteers

Back to Top


Nutrient Content

Chinese Skullcap root contains numerous bioactive compounds with varying concentrations depending on harvesting conditions, processing methods, and plant age:

Primary flavonoids content (typical ranges):

  • Baicalin: 8-15% of dried root weight
  • Baicalein: 1-5% of dried root weight
  • Wogonoside: 1-3% of dried root weight
  • Wogonin: 0.5-2% of dried root weight
  • Oroxylin A: 0.2-1% of dried root weight
  • Scutellarin: 0.5-2% of dried root weight

Additional components:

  • Volatile oils: 0.1-0.5% of dried material
  • Polysaccharides: 2-8% of dried root
  • Amino acids: 14 different types identified
  • Sterols: β-sitosterol and α-spinasterol
  • Trace elements: Including platinum concentrated in roots
  • Phenolic acids: Citric acid, tartaric acid, malonic acid

Back to Top


How Sold

Chinese Skullcap is available commercially in various forms:

  • Dried root pieces for traditional decoctions
  • Standardized extracts (liquid and powder)
  • Capsules and tablets (often standardized to baicalin content)
  • Tinctures and liquid preparations
  • Granules for easy preparation
  • Traditional Chinese medicine formulations
  • Combination products with other herbs
  • Topical preparations for skin conditions
  • Veterinary formulations for animal use

Products are typically standardized to contain specific percentages of baicalin or total flavonoids. Quality can vary significantly between manufacturers, and products should be obtained from reputable sources that provide third-party testing for purity and potency.
Back to Top


Warning

Important Safety Information:

General Safety: Chinese Skullcap is possibly safe for most adults when taken by mouth for up to 8 weeks. However, it may cause stomach pain, constipation, vomiting, and stomach upset in some individuals.

Serious Product Concerns: One specific product (Limbrel, Primus Pharmaceuticals) containing a mixture of Chinese Skullcap and catechu has been linked to serious side effects including multiple reports of liver and lung injury. The US FDA recalled this product in 2017 due to serious safety concerns.

Pregnancy and Breast-feeding: There isn’t enough reliable information to know if Chinese Skullcap is safe during pregnancy or breast-feeding. Stay on the safe side and avoid use.

Bleeding Disorders: Chinese Skullcap might slow blood clotting and increase the risk of bruising and bleeding in people with bleeding disorders.

Hormone-Sensitive Conditions: Chinese Skullcap might have estrogen-like effects. If you have breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids, avoid use as it might worsen these conditions.

Surgery: Stop using Chinese Skullcap at least 2 weeks before scheduled surgery as it might cause extra bleeding during and after surgery.

Allergic Reactions: Baicalin has been identified as a potential allergen that can cause allergic reactions mediated by IgG and IgE antibodies. Some individuals may develop contact dermatitis from topical use.

Liver Toxicity: High doses have shown potential hepatotoxicity in animal studies, with reversible inflammatory changes in liver tissue at very high doses (2500 mg/kg/day).

Drug Interactions:

  • Blood Thinners (Warfarin, Anticoagulants): May increase bleeding risk
  • Statins: May decrease blood levels of cholesterol-lowering drugs
  • Diabetes Medications: May cause blood sugar to drop too low
  • Blood Pressure Medications: May cause blood pressure to go too low
  • Lithium: May decrease lithium elimination, leading to serious side effects
  • Estrogens: May decrease the effects of estrogen pills
  • CYP450 Substrate Drugs: May change metabolism of medications processed by liver enzymes CYP1A2 and CYP2C19
  • Thyroid Medications: May affect how antithyroid medications work
  • Sedative Medications: May cause excessive sleepiness and breathing problems

Special Populations: Individuals with spleen and stomach deficiencies may find Chinese Skullcap unsuitable due to its bitter and cold medicinal characteristics according to TCM theory.

Always consult with a qualified healthcare provider before using Chinese Skullcap, especially if you have existing health conditions, are taking medications, or are pregnant or nursing. Natural products are not always necessarily safe, and dosages can be important.
Back to Top


Resource Links

Herbal Medicine Shows Promise in Liver Cancer Treatment Analysis

Frontiers in Oncology – Effectiveness of herbal medicine for liver cancer treatment as revealed by a bibliometric and visualization analysis

Traditional Medicinal Plants Used by Tujia People in Guizhou

Frontiers in Pharmacology – Medicinal plant use by the Tujia people in northeastern Guizhou, China: an ethnobotanical study

Memorial Sloan Kettering Cancer Center – Scutellaria baicalensis

ScienceDiredt – An updated review of Chinese skullcap (Scutellaria baicalensis): Emphasis on phytochemical constituents and pharmacological attributes

ScienceDirect – Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants

National Library of Medicine – The Use of Chinese Skullcap (Scutellaria baicalensis) and Its Extracts for Sustainable Animal Production

WebMD – Baikal Skullcap – Uses, Side Effects, and More

BioMedCentral – Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review

Drugs.com – Baikal Skullcap

Back to Top




Share
  • gaming & herbalism
    The Intersection of Gaming and Herbalism Herbs
  • CreoleChemist Revolutionizes Natural Healing with Plant-Based Medicine Expertise In the News
  • orangutan
    Wild Orangutan Spotted Using Medicinal Plant for Self-Care In the News
  • Broccoli
    Broccoli’s Cancer-Fighting Potential Revealed Healing
  • turmeric
    Top 12 Ayurvedic Herbs and Their Surprising Health Benefits Ayurveda
  • Exotic Herbs in Prime Time Again Herbs
  • plants can feel touch
    Plants Can Sense Touch and Respond to Pressure In the News
  • Cancer Treatment that ‘Reboots’ Itself, Thanks to This Herb Healing

Copyright © 1996-2025 Medicinal Herb Info. All Rights Reserved

Powered by PressBook Premium theme